This study attempts to understand the meaning and context of biology teachers’ and high school students’ interest experiences in biology class through the phenomenological qualitative approach. Data was collected from 4 biology teachers and students through in-depth interview and analyzed to find out the significance of the experience of interesting biology class. As a results, a total of 15 themes and 4 categories,‘not interesting or only interesting class’,‘students experiences in interesting biology class’,‘teacher’s efforts to lead interesting biology class’,‘interest that teacher and students form together’, were revealed. These results showed that interest of biology class was not a mere experience of laughing during class, but a satisfying experience composed of cognitive, emotional, social, and sensory factors.