Purpose: This study was designed to construct a structural model for family function of the family with chronic mental disorder. Method: The hypothetical model was developed based on the literature review. Data were collected by questionnaires from 365 the family with chronic mental disorder a National Mental Health Hospital and a General Hospital. Data analysis was done with SAS 6.12 for descriptive statistics and PC-LISREL 8.0 Program for Covariance structural analysis. Result: The fit of the hypothetical model to the data was moderate, thus it was modified by excluding 6 path and including free parameters to it. The modified model with path showed a good fitness to the empirical data(x2=339.84, p=0.0, GFI=.98, AGFI=.90, NNFI=.95, RMSR=.01, RMSEA=.04). The family hardiness, sense of coherence, and the family coping were found to have significant direct effect on family function of the family with chronic mental disorder. The pile-up stress were found to have indirect effects on family function of the family with chronic mental disorder. Conclusion : The derived model in this study is considered appropriate in explaining and predicting family function of the family with chronic mental disorder. Therefore it can effectively be used as a reference model for further studies and suggested direction in nursing practice.