Background: The incidence of basal cell carinoma (BCC) has increased in the last decade and is still increasing. Many treatment modalities have been used to treat BCC. Mohs micrographic surgery (MMS) is a specialized type of minimal marginal surgery that offers cure rates superior to other options in the treatment of skin cancers, including BCC. Objective: The purpose of this study is to report our experience of MMS for the treatment of facial BCC and to identify clinical and histological characteristics of BCC treated by MMS. Methods: We analyzed 43 cases of BCC treated by MMS at the Department of Dermatology, Chonnam National University Hospital in Gwangju between March 2003 and September 2005. Results: The mean duration of BCC was 2.5 years, and the mean size was 11.6㎜. The most frequent clinical type of BCC was the pigmented type (44.2%), followed by noduloulcerative (34.9%), and morpheaform type (20.9%). The most common site was the nose (58.1%), followed by the lip (14.0%), eyelid (9.3%), and cheek (7.0%). The most frequent histologic pattern was the nodulocystic type (39.5%), followed by the infiltrative (18.6%), microcystic (11.6%), mixed (11.6%), metatypical (9.3%), and the adenoid type (9.3%). The local flap was the most common method to repair surgical defects (67.4%), followed by primary closure (25.6%), and skin graft (7.0%). None of the cases recurred during 15.2 months (range: 1.5 to 30 months) follow up. Conclusion: Further study will be required for the difference in the rate of curability according to the type of facial BCC treated by MMS. (Korean J Dermatol 2006;44(6):721~726)