Study objects: This study is to investigate nurses` perception to the patient safety in hospital, in order to provide the patient with the more safe medical care services. Methods: This study method used the Hospital Survey on Patient Safety Culture developed by AHRQ(2004) to investigate nurses` perception to the of patient safety in hospital. This survey was conducted to the 359 nurses in university hospital. Result: The result of this study are as follows. First, nurses` perception to the patient safety culture in hospital shows generally on the average score(3.16±.29). Among three categories, Patient Safety in Ward(Work Area/Unit), patient safety within hospital and reporting procedures on error related to the patient safety, patient safety within hospital was the highest score(3.37). Second, the correlation between patient safety in ward(work arealunit), patient safety within hospital and safety perception, safe and reporting system showed positive relationship. The relationship between safety perception, reporting completeness and openness on communication within hospital was most positive relation. Third, nurses` recognition to the patient safety Is very different by respondent`s characteristics. Conclusion In order to improve the patient safety in hospital, the active measures were developed in efficient communications within hospital.