Mild Cognitive Impairment(MCI) often represents a transitional stage betweeen normal aging and Alzheimer`s Disease(AD). Review of many studies of MCI and AD, The overall pattern of neuropsychiatric symptoms in MCI is similar to that seen in mild AD, with depression, apathy, agitation, anxiety, and irritability among the most commonly exhibited symptoms. Several longitudinal studies of MCI suggest that depression and apathy in particular may represent prodromal symptoms of AD that are indicative of subsequent development of dementia, althougth not all investigators have confirmed these findings. These symptoms have serious adverse consequences and should be inquired about and treated as necessary.