Ischemia of active skeletal muscle elicits the pressor response that termed the muscle metaboreflex (MMR). It is suggested that the MMR plays an important role in regulating cardiovascular responses during dynamic exercise. However, it has not been investigated that chronic aerobic exercise training modulate the pressor response mediated by the MMR. Eleven sedentary college students (CG) and eleven age-matched college soccer players (CPG) were recruited for this study. We measured systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and stroke volume (SV) at rest and during hand grip static exercise and post exercise muscular ischemia (PEMI) in both group. Mean arterial pressure (MAP), cardiac output (CO), and total vascular conductance (TVC) were calculated. SBP, DBP, MAP were increased during static exercise, however, there were no differences between two group. SBP, DBP, MAP were increased during PEMI, however, the increase in SBP, DBP and MAP in CPG were attenuated compared to CG. Even though both SV and CO significantly increased, there were no differences in HR, SV, and CO responses between two group during static exercise and PEMI. TVC was significantly increased in CPG during static exercise compared to CG. With PEMI, There was no change in CPG, while there was significantly decrease in CG. even thouge due to higher increase of total peripheral resistance during passive stretch. This study suggests that the attenuated blood pressure response mediated by the MMR in CPG may be due to peripheral vasodilation despite an increase in CO. The chronic aerobic exercise training may improve function of the MMR.