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> 한국미생물생명공학회(구 한국산업미생물학회) > 한국미생물·생명공학회지 > 40권 2호

35종 해조류 추출물의 병원성 세균 및 Candida sp. 진균에 대한 항균 활성 평가

Evaluation of the Antimicrobial Activities of 35 Seaweed Extracts against Pathogenic Bacteria and Candida sp..

김미선 ( Mi Sun Kim ) , 권경진 ( Kyung Jin Kwon ) , 이민진 ( Min Jin Lee ) , 안선미 ( Seon Mi Ahn ) , 손호용 ( Ho Yong Sohn )

- 발행기관 : 한국미생물생명공학회(구 한국산업미생물학회)

- 발행년도 : 2012

- 간행물 : 한국미생물·생명공학회지, 40권 2호

- 페이지 : pp.144-151 ( 총 8 페이지 )


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4,500
논문제목
초록(외국어)
In the course of this study aimed at the development of functional food ingredients from seaweeds, the in vitro antimicrobial activities of methanol extracts prepared from 35 different seaweeds (17 phaeophyta, 11 rhodophyta and 7 chlorophyta) were determined against food-borne diseases and pathogenic microorganisms including multi-drug resistant (MDR) Pseudomonas sp. and Candida sp. Based on disc-diffusion assays at 500 g/disc concentration of the methanol extracts, Ishige okamurai, I. foliacea, Sargassum confusum, and S. yamade exhibited strong antibacterial activities in a broad-spectrum, except against Pseudomonas aeruginosa. In addition to the latter four seaweeds, Ecklonia stolonifera, E. cava and Eisenia bicyclis also demonstrated antifungal activity against C. albicans. Among these 8 selected seaweeds, I. okamurai, I. foliacea, and S. yamade exhibited strong hemolytic activity (55-93%) at 500 g/ml against human RBC. Organic solvent sequential fractions using hexane, ethylacetate and butanol, and water residues were prepared from the 8 selected seaweeds and their anti-Candida sp. activities were further determined. The ethylacetate and butanol fraction of I. okamurai, and the hexane fraction of I. foliacea demonstrated antifungal activity against MDR-pathogenic Candida sp. Although the solvent fractions had no activity against MDR-Pseudomonas sp., our results suggest that seaweeds, especially Ishige okamurai, I. foliacea, S. confusum, and S. yamade could be developed as broad-spectrum antimicrobial ingredients.

논문정보
  • - 주제 : 자연과학분야 > 생물
  • - 발행기관 : 한국미생물생명공학회(구 한국산업미생물학회)
  • - 간행물 : 한국미생물·생명공학회지, 40권 2호
  • - 발행년도 : 2012
  • - 페이지 : pp.144-151 ( 총 8 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2012-470-003092385
저널정보
  • - 주제 : 자연과학분야 > 생물
  • - 성격 : 학술지
  • - 간기 : 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : - / SCOPUS
  • - ISSN : 1598-642x
  • - 수록범위 : 2002–2020
  • - 수록 논문수 : 1112