This study was conducted to investigate the clear concept of proactivity of people with mental disabilities and to provide basic evidence for mental health nursing. Methods: The research was conducted using Walker & Avant``s conceptual analysis process. Results: Proactivity of people with mental disabilities is defined as the ability of obtaining self-determination by putting continuous efforts toward their recovery, overcoming social stigma, recovering in a positive way from being withdrawn from relationships, and gaining self-confidence and willingness that they can recover from their mental illness. Antecedents were found to be persistent disease management, active participation and support of significant person. Consequences were found to be maintenance of a productive life. Conclusion: The results of this study accurately define the vague concept of proactivity of people with mental disabilities and contribute to mental health nursing related to proactivity for people with mental disabilities.