Location problem of reverse-logistics is the foundation and key in reverse-logistics system. Therefore, it is a great task with practical meaning to study how to determine the scheme of location problem of reverse-logistics. Based on the background hereinbefore, we did a study on reusing system of reusable logistics circulation cases. We modeled a turnover process of circulation cases by means of leasing, which considered clustering of the shortest distance between demand stations, recovering stations and delivery destinations. Genetic algorithm is adopted to find the optimization solution. Except to design circulation cases reverse-logistics system, the researching progeny could use to design other packing containers reverse-logistics system, such as freight containers and pallets.