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> 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) > Allergy Asthma & Respiratory Disease > 1권 3호

2세 이하 아토피피부염 환아에서 비타민 D 부족과 식품항원 감작의 연관성

ORIGINAL ARTICLE : Vitamin D insufficiency is associated with food sensitization in children under 2 years with atopic dermatitis

백종욱 ( Jong Uk Baek ) , 황보준원 ( Jun Won Hwangbo ) , 이혜란 ( Hae Ran Lee ) , 이소연 ( So Yeon Lee )

- 발행기관 : 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회)

- 발행년도 : 2013

- 간행물 : Allergy Asthma & Respiratory Disease, 1권 3호

- 페이지 : pp.211-215 ( 총 5 페이지 )


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논문제목
초록(외국어)
Purpose: Vitamin D levels are known to be associated with development of allergic diseases. However, existing data are controversial. The aim of this study was to investigate whether vitamin D levels are associated with food sensitization (FS) in young children with atopic dermatitis (AD). Methods: We performed a medical record review of all patients under 2 years presenting to pediatric allergic clinic in Hallym University Sacred Heart Hospital for atopic dermatitis between March 1, 2012 and February 28, 2013. Serum 25-hydroxyvitamin D (25(OH)D) levels and six specific immunoglobulin E (IgE) to common food allergens were measured in 132 young children with AD. We defined vitamin D insufficiency was 25(OH)D <30 ng/mL, and FS as specific IgE ≥0.35 IU/mL to any of six common food allergens. Associations between serum 25(OH)D levels and FS were examined by using multiple logistic regression, adjusting for potential risk and confounding factors. Results: The mean age was 10.1 months. Among the 132 children with AD, 65.9% had FS. In this group, there was a negative correlation between 25(OH)D levels and serum eosinophil percentage (correlation coefficient [r]=.0.335, P<0.01), but not correlated with serum total IgE levels. Children with vitamin D insufficiency were more likely to have FS (adjusted odds ratio, 17.1; 95% confidence interval, 1.36 to 215; P=0.028) than those with adequate vitamin D levels. Conclusion: Vitamin D insufficiency is associated with FS in young children with AD. Further research is needed to confirm these findings. (Allergy Asthma Respir Dis 2013;1:211-215)

논문정보
  • - 주제 : 의약학분야 > 소아과학
  • - 발행기관 : 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회)
  • - 간행물 : Allergy Asthma & Respiratory Disease, 1권 3호
  • - 발행년도 : 2013
  • - 페이지 : pp.211-215 ( 총 5 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2015-500-000272506
저널정보
  • - 주제 : 의약학분야 > 소아과학
  • - 성격 : 학술지
  • - 간기 : 격월
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : -
  • - ISSN : 2288-0402
  • - 수록범위 : 2013–2015
  • - 수록 논문수 : 208