This paper illustrates how Neal Stephenson``s cyberpunk fiction Snow Crash (1992) recreates the transformation from the human to the posthuman through the possibility of human and machine interface in a virtual reality, and connects this to other interdisciplinary fields to create new ideas of their interrelations through rapid technical development. I focus on the interaction between the human brain and the computer to reflect high scientific technology within the current historical moment, in which the infinity of the cyberspace is articulated through the cybernetic metaphor. I explain correlations of human acquired language and computer languages like assembly or programming language, and a hacker and a computer virus, snow crash which is a kind of computer language. The Metaverse and avatars reflect not only cybernetic technology, but also express new ideas about the human nature, science, cyberpunk culture and their respective combination in the near future. In Snow Crash characters like cyborg interact with software programs, in a three dimensional cyberspace that uses the metaphor of the real world. Stephenson in the unstoppable advances of the culture of web and internet, suggests some solutions to the problems and desires to contemplate how virtual reality systems affect our lives because nowadays, realms of our lives in a virtual reality enlarge continually.