The independent living of people with disabilities by assistive technology is an important service that allows disabled people to have an opportunity to have their jobs and contribute to the community. Prior studies have demonstrated the need for assistive technology, but the effectiveness of this assistive technology for the disabled workers in employment cases has not been researched in depth so far. By the technology acceptance model, this study first identifies influencing factors for the successful deployment of assistive technology to disabled workers, and then it finds the relationship among those factors for their adaptation in work environments in terms of their behavioral intention. The purpose of this study is to show the following two facts. First, the employment of disabled workers can improve the capacity and quality of their lives. Second, it can obtain additional human resources for employers through the quality of support by assistive technology. Disabled workers in this study are the population of domestic firms or domestic industry participating in only one cluster involved in business enterprises, who are systematically targeted survey samples extracted from Seoul, metropolitan area, and Chungcheong region.