This study considers the sound of Sino-Korean in The Korean Annotation of Mark in the New Testament from a contrastive perspective, which is recognized as an accurate and detailed early Korean Bible, which marked an important word with Chinese character and Sino-Korean, that in the front and this in the rear. The feature of the initial is as follows: 1. There is an example whose initial xi 溪 is marked as ``ㅇ``(``교``). 2. There are a few examples whose initial ni, niang 泥·娘 are marked as ``ㅇ``(``女·溺``). 3. The initial lai 來 is marked as ``ㄴ`` or ``ㅇ``(``論·來·雷·람·靈·櫓; 禮·六·離·立· 臨``). 4. There are a few examples whose initial group zhengchi 正齒 mingle ``ㅈ`` and ``ㅅ``(``詐·時``). 5. The initial ri 日 is all marked as ``ㅇ`` (``然·熱·二·爾·耳·日·任·入``). 6. The initial group shetou, sheshang 舌頭·舌上 of the third and fourth division is all palatalized and marked as ``ㅈ`` or ``ㅊ``(``地·置·致·陳·馳``). The feature of the final is as follows: 1. The first and second division of rhyme hai·hui 해·灰 and jie·jia·kuai·tai 皆·佳·쾌·泰 of rhyme group Xie 蟹攝 and the second division of rhyme group geng 梗 攝 are marked as ``ㆎ`` and ``ㅁ``(``改·在·海·碍·倍·杯·妹·對·內·悖; 偕·拜·駭·解·芥·賣·大·害; 行·盟·萌·爭·責``). 2. The third division of rhyme group zhi 止攝 mingles with that of double rhyme 重紐 and is marked as ``ㅢ``(``己·記·期·起·忌·旣·祈·醫·疑·意·衣; 器· 奇·義·議``). The rhyme zhi 之 ``其`` and the initial yi 以 ``異`` are marked as ``ㅣ``. 3. The initial group chitou 齒頭 and zhengchi erdeng 正齒2等 are marked as ``ㆍ``(``資·自·子``), and some examples are marked as ``ㆍ`` or ``ㅏ`` at the same time (``四·賜·자·事·士·使``). 4. The third and fourth division of initial group chi 齒 has a semi-vowel ``ㅣ``[-j-] in middle and modern Sino-Korean, but some examples do not have it in The Korean Annotation of Mark in the New Testament (``請; 就; 相·上·誓·聽· 長·蟲``). 5. There are a few examples in which the ending -ŋ of the third division rhyme geng 庚 and qing 淸 of rhyme group geng 梗攝 is marked as -n(``命·餠``), and the ending -k of the third division rhyme zhi 職 of rhyme group zeng 曾攝 as -p(逼).