Purpose: This study was done to identify variables in Attention Deficit Hyperactivity Disorder (ADHD) symptoms and negative ideation that predict interpersonal relation in adults. The focus was on thought, behavior, emotional and cognition domains. Methods: Korean Conner``s Adult ADHD Rating Scale, Anxious Thought Inventory, Interpersonal Relation Scale were used. Participants were 379 of normal adults living in B, I and U cities. The data were analyzed using frequency, F-test, t-test, ANOVA, Scheffe and Pearson``s correlation coefficients. Regression analysis was done to provide understanding of the effects of each variable. Results: Interpersonal relation showed significantly negative correlation with adult related ADHD symptoms and negative ideation. Significant predictive factors of interpersonal relation were social-worry (β=-.40), inattention/memory problems (β=-.22) and gender (β=-.12) in order. These variables accounted for 25% of variance in interpersonal relations. Conclusion: The results show that social-worry in the cognitive domain and inattention-memory problems in the thought domain have a negative impact on interpersonal relation in adults compared` to the behavior or emotional domains which indicates a need for intervention strategies to reduce inattention/memory problems and social-worry and thus improve interpersonal relations.