Purpose: The objectives of the study were to examine university students`` health behavior, depression, and ego-resilience in order to understand the relationship between these variables, and to identify factors influencing egoresilience. Methods: Data were collected from a sample of 302 students attending G University. The data collection period was from October 28, 2015 to December 21, 2015. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson``s correlation coefficients, and multiple regression with the SPSS Statistics version 23 Program. Results: The number of close friends was weakly correlated with depression and ego-resilience: specifically, the number of close friends had a weak negative correlation with depression, and a weak positive correlation with ego-resilience. Factors significantly influencing the students`` ego-resilience were depression, type of residence, frequency of exercise, and gender, with a total explanatory power of 18%. Conclusion: These findings indicate that intervention programs to improve ego-resilience should be developed. Research into ego-resilience should be replicated with students from a variety of cultural background and diverse study areas.