Objective: The purpose of this study was to investigate the effect of an 8-week ProBody massage programon body alignment and plantar pressure balance in middle-aged men with musculoskeletal diseases.Method: The subjects of this study were 20 middle-aged men with musculoskeletal diseases in B MetropolitanCity who participated in an 8-week ProBody massage program conducted twice a week. Physical characteristics(height, weight, and body mass index), body alignment, and plantar pressure were assessed before andafter the experiment.Results: The 20 middle-aged men with musculoskeletal diseases who underwent the ProBody massageprogram showed positive changes in physiological characteristics, body alignment, and plantar pressurebalance.Conclusion: Consequently, the 8-week ProBody massage program was suggested to be effective forimproving and preventing postural imbalance in middle-aged men with musculoskeletal diseases. TheProBody massage program could also be utilized to improve the body alignment and plantar pressurebalance in middle-aged women with musculoskeletal diseases.