The purpose of this paper was to identify the correlations among academic stress and adjustment at university life in university students. Methods: A total of 489 subjects aged 17 and 36 were selected through convenient sampling. Data were collected with a self reported questionnaire from September 2 to November 30, 2015. Collected data were analyzed with SPSS/WIN. Results: There were statistical differences between academic stress and adjustment at university life. Academic stress were significantly different according to gender, grade, economic status, health status major department of study, drinking and smoking. Adjustment at university life were significantly different according to gender, economic status, health status. 25.4% of variance in adjustment at university life were explained by academic stress, major department of study, health status. Conclusion: The finding of this study may be useful in understanding the academic stress expression of university students and developing more specific programs on adjustment at university life.