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S-646 A Case of Aplastic anemia in a Chikungunya fever patient
( Jeongmin Hong ) , ( Sung-bok Ji ) , ( Hee Cheul Jung ) , ( Yoomee Kang ) , ( Oh-hyun Cho )
UCI I410-ECN-0102-2017-510-000530161

Chikungunya is an arthropod-borne tropical disease whose most common symptoms are fever and arthralgia. Although hematologic abnormal findings, such as anemia and lymphocytopenia, are not uncommon in Chikungunya, aplastic anemia has never been reported in literature. Here, we describe the case of Chikungunya who developed aplastic anemia during the course of disease. A 28-year-old Parkistani man was admitted with two weeks history of fever, headache, and myalgia. His complete blood counts showed pancytopenia with hemoglobin 5.4 g/dL, white blood cell count 3,920/mm3, and platelet count 88,000/mm3. Chikungunya was diagnosed by positive IgM for chikungunya virus by enzyme-linked immunosorbent assay. Because anemia and thrombocytopenia persisted for about 2 months, the bone marrow examination was performed. After a diagnosis of aplastic anemia was made by a less than 10 percent cellularity on the bone marrow examination, the patient was treated successfully using high dose steroid. Our case suggests that aplastic anemia can be a rare complication of chikungunya virus, and it must be included the differential diagnosis of anemia if the symptom is persistent.

[자료제공 : 네이버학술정보]
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