This essay examines Francis Godwin`s seventeenth-century configurations of plants, animals, and machines in The Man in the Moone: or A Discourse of a Voyage Thither by Domingo Gonsales the Speedy Messenger. It investigates human-nonhuman relationships and the possibility of nonhuman agency as exemplified within the text. In contrast to previous scholarly readings of the text as a prototypical early modern lunar voyage narrative, this essay focuses on Gonsales`s unusually entangled relationships with botanical and zoological species in such liminal places as St Helena and the moon. Gonsales, in cataloging a variety of plants, animals, and their seasonal behavior, illustrates not only an anthropocentric way of producing knowledge in the allegedly colonial site, but also his increasing awareness of nonhuman agency and his multi-layered implications with them. Equally importantly, Gonsales`s use of wild fowls―what he calls gansas―as a flying machine signals a culmination of early modern technological imagination. In exploring Gonsales`s inter-special relationships and technological imagination, ones reflecting major shifts in early modern inventions and knowledge-making as exemplified in Francis Bacon`s Novum Organum, this essay asserts that Godwin`s seventeenth-century fantastic voyage, in effect, suggests that accumulative knowledge of nonhuman others might entail both affective and cognitive understandings of them.