Purpose: The purposes of this study were to develop an acceptance commitment-based cognitive behavioral program for patients with schizophrenia and to use it as an intervention tool for psychiatric mental health nursing and thereby confirm the program’s effects on patients’ psychological flexibility, psychological well-being, and treatment adherence including insight and attitude toward treatment. Methods: This study consisted of a pretest, posttest 1, and posttest 2 for a nonequivalent control group design. The participants were 42 patients with schizophrenia (experimental group: 21, control group: 21). The acceptance commitment-based cognitive behavioral program was conducted in 10 sessions for 5 weeks. Data collected from February to April 2018 were analyzed using the SPSS/WIN 25.0 for x2 test, Fisher’s exact test, independent t-test, and repeated measurement ANOVA. Results: The differences between experimental and control groups were statistically significant regarding psychological flexibility, psychological well-being, and insight. Conclusion: This study findings suggest that the acceptance commitment-based cognitive behavioral program can be used as an effective mental health nursing intervention for psychological flexibility, psychological well-being, and insight of patients with schizophrenia.
