It is understood that air pollutants have a negative impact on human health and the quality of life. Therefore, it is essential to explore the determinants of urban air pollutants in the neighborhood in which we live. However, few studies have investigated the fine particulate matter(PM2.5), which has been seriously discussed recently. Therefore, this study aims to identify the influences of neighborhood built environment on air pollutants including NO₂, SO2, O₃ as well as PM_2.5. Air pollutant data was based on the yearly average value of 2014 provided by Seoul Air Quality Information. As a result of the Moran’s I test, spatial autocorrelation was not detected and the general regression model was employed. The main results are as follows; the influences of built environment differ depending on air pollutants. SO₂ and O₃ were high in the neighborhood with many industrial areas. PM_2.5 and NO₂ were high in the neighborhood with main roads and average total floor area of commercial areas. but low in the neighborhood with more multi-family housing. Street trees had a negative association with SO₂, while the bus stations had a positive relationship. This study will be helpful to establish urban planning and environmental policies and interventions to build eco-friendly and healthy Seoul city.