This study demonstrates the importance of syntagmatic relations(colloquial relations) with respect to vocabulary instruction and discusses its application methods. Using a group of the marked measure adjectives such as “large”, “many”, “wide”, “deep”, “high”, “severe”, “heavy”, “thick” and “strong”, which are usually found in measure expressions related to size, volume and width, this study attempts to apply the colloquial relations to developing a vocabulary teaching method that can differentiate their usages. In this study, it is found that foreign learners are likely to make errors because the colloquial relations in these measure adjectives are different from those used in their mother languages. Overall, this study not only provides the contents knowledge regarding the syntagmatic vocabulary relations but also suggests specific teaching methods that can be applied in vocabulary instruction. (Yonsei University)