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> 생화학분자생물학회 > BMB Reports > 26권 5호

Original Articles ; Cell Cycle Dependent Expression of cdc2 During Rat Liver Regeneration

Original Articles ; Cell Cycle Dependent Expression of cdc2 During Rat Liver Regeneration

In Sung Song , Chung Ho Hong , Hee Won Lee , Sung Ki Lee Kyung Hee Choi , Doe Sun Na

- 발행기관 : 생화학분자생물학회

- 발행년도 : 1993

- 간행물 : BMB Reports, 26권 5호

- 페이지 : pp.460-464 ( 총 5 페이지 )


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논문제목
초록(외국어)
The cdc2 gene encodes a 34 kDa protein (p34^(cdc2)) which is a protein kinase and plays a regulatory role in the cell cycle. To study the regulation of cdc2 in regenerating rat liver, we have cloned rat cdc2 cDNA from a rat liver cDNA library. The nucleotide sequence of the coding region, and the deduced amino acid sequence for 297 residues, show, respectively, 94.1% and 99.3% homologies to mouse cdc2. Expression of cdc2 during the first cell cycle of rat liver regeneration after partial hepatectomy was investigated. The level of mRNA was low until entry into S phase, increased to a maximum during S and G2 phase, decreased during M phase, and dropped to the background level upon exit from M phase. The pattern of p34^(cdc2) activity level change was similar to the that of mRNA.

논문정보
  • - 주제 : 자연과학분야 > 화학
  • - 발행기관 : 생화학분자생물학회
  • - 간행물 : BMB Reports, 26권 5호
  • - 발행년도 : 1993
  • - 페이지 : pp.460-464 ( 총 5 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2008-470-002206719
저널정보
  • - 주제 : 자연과학분야 > 화학
  • - 성격 : 학술지
  • - 간기 : 월간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : - / SCOPUS
  • - ISSN : 1976-6696
  • - 수록범위 : 1968–2022
  • - 수록 논문수 : 4652