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> 한국생약학회 > Natural Product Sciences > 13권 1호

Synergism in Antifungal Activity against Candida and Trichophyton Species in Combination with the Essential Oil of Coriandrum sativum L. and Antibiotics

Synergism in Antifungal Activity against Candida and Trichophyton Species in Combination with the Essential Oil of Coriandrum sativum L. and Antibiotics

( Lim Sook ) , ( Seung Won Shin )

- 발행기관 : 한국생약학회

- 발행년도 : 2007

- 간행물 : Natural Product Sciences, 13권 1호

- 페이지 : pp.85-89 ( 총 5 페이지 )


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초록(외국어)
To determine whether the essential oil from Coriandrum sativum and its main component, linalool, exhibit antifungal activity, we employed a broth dilution assay and disk diffusion test using common pathogenic Candida and Trichophyton species. Both coriander oil and linalool significantly inhibited growth of the tested fungi, with minimal inhibitory concentrations (MICs) in the range of 0.03~2 mg/ml. Furthermore, in a checkerboard titer test, both the oil fraction and linalool exhibited synergism when combined with ketoconazole, with resultant FICIs ranging from 0.06 to 0.53. Notably, hyphal formation in C. albicans cells was obviously inhibited by C. sativum essential oil in this experiment.

논문정보
  • - 주제 : 의약학분야 > 약화학
  • - 발행기관 : 한국생약학회
  • - 간행물 : Natural Product Sciences, 13권 1호
  • - 발행년도 : 2007
  • - 페이지 : pp.85-89 ( 총 5 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2008-510-002842716
저널정보
  • - 주제 : 의약학분야 > 약화학
  • - 성격 : 학술지
  • - 간기 : 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : - / SCOPUS
  • - ISSN : 1226-3907
  • - 수록범위 : 1995–2021
  • - 수록 논문수 : 1174