Purpose: The present study was to identify health status, health behavior and quality of life(QOL) in the elderly aged over 65 years with osteoarthritis compared with those of the healthy elderly. Methods: We analysed data from 326 elderly drawn from the Forth Korea National Health and Nutrition Examination Survey 2009 performed by Ministry of Health and Welfare and Korea Centers for Disease Control and Prevention: 244 elderly with osteoarthritis and 82 healthy elderly without chronic diseases. Results: The elderly with osteoarthritis were more likely to be female, no spouse, low educational level, low subjective health status and low functional health status. The elderly with osteoarthritis were found to have lower smoking, lower alcohol consumption and more obesity than those of the healthy elderly. Walking physical activity was not different between the elderly with osteoarthritis and the healthy elderly. Finally, the elderly with osteoarthritis were found to have lower mobility, lower usual activities, more pain/discomfort, and more anxiety/depression among EQ-5D(Euro Quality of Life-5 Dimension) health profiles, lower EQ-5D index and lower EuroQoL-VAS mean. Conclusions: The elderly with osteoarthritis were at high risk for poor QOL. It is necessary to supply a comprehensive management program to improve QOL for the elderly with osteoarthritis.