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> 대한피부과학회 > 프로그램북(구 초록집) > 65권 2호

P139 : Anti-wrinkle effect of stem cell conditioned media

P139 : Anti-wrinkle effect of stem cell conditioned media

( Min Young Jung ) , ( Hee Chul Chung ) , ( Dong Hye Kim ) , ( Hye Rin Jeon ) , ( Hyun Soo Kim ) , ( Yong Man Kim ) , ( Eung Ho Choi )

- 발행기관 : 대한피부과학회

- 발행년도 : 2013

- 간행물 : 프로그램북(구 초록집), 65권 2호

- 페이지 : pp.378-378 ( 총 1 페이지 )


학술발표대회집, 워크숍 자료집 중 1,2 페이지 논문은 ‘요약’만 제공되는 경우가 있으니,

구매 전에 간행물명, 페이지 수 확인 부탁 드립니다.

1,000
논문제목
초록(외국어)
Background: Bone marrow-derived mesenchymal stem cell (BM-MSC) is a representative and classic stem cell applied widely for clinical aspects, especially in the fields of myocardial and hepatic regeneration. Objectives: This clinical trial aims to evaluate the anti-wrinkle effect and safety of BM-MSC conditioned media. Methods: The tried cosmetic product contains the active ingredients of BM-MSC conditioned media, while the control product has no active ingredients. 29 subjects were finally selected and randomly applied each product to the left or right side of the face twice a day for 8 weeks. Results: The participants were women aged between 36 and 55 with the average age of 43.7. In visual evaluation, 13 subjects showed better results on the treated area, whereas 8 subjects on the control area. Based on clinical pictures, there was a significant wrinkle reduction rate on the treated area. The wrinkle reduction rate on the treated area was 12.0% on average, compared with -1.25% on the control area in 4 weeks (p<0.001), and 23.31% on the treated area compared with 3.84% on the control area in 8 weeks (p<0.001). In replica analysis, significant decreases in wrinkles length (8 weeks) and wrinkles depth (4 and 8 weeks) were identified in treated area. Only a few mild side-effects were associated with BM-MSC conditioned media. Conclusion: In conclusion, an anti-wrinkle cosmetic product with BM-MSC conditioned media could significantly improve wrinkles with less and very slight side-effects.

논문정보
  • - 주제 : 의약학분야 > 피부과학
  • - 발행기관 : 대한피부과학회
  • - 간행물 : 프로그램북(구 초록집), 65권 2호
  • - 발행년도 : 2013
  • - 페이지 : pp.378-378 ( 총 1 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2014-500-001913024
저널정보
  • - 주제 : 의약학분야 > 피부과학
  • - 성격 : 학술발표
  • - 간기 : 반년간
  • - 국내 등재 : -
  • - 해외 등재 : -
  • - ISSN :
  • - 수록범위 : 1947–2021
  • - 수록 논문수 : 24140