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> 한국생약학회 > Natural Product Sciences > 19권 3호

Articles : Evaluation of the Effects of Acorus gramineus and Acorus tatarinowii Extracts on a Rat Model of Arterial Thrombosis induced by Ferric Chloride

Articles : Evaluation of the Effects of Acorus gramineus and Acorus tatarinowii Extracts on a Rat Model of Arterial Thrombosis induced by Ferric Chloride

( Ji Hye Bang ) , ( Ki Mo Lee ) , ( In Sun Lee ) , ( Eun Jung Heo ) , ( Hyung Won Kang ) , ( Won Kyung Jeon )

- 발행기관 : 한국생약학회

- 발행년도 : 2013

- 간행물 : Natural Product Sciences, 19권 3호

- 페이지 : pp.251-257 ( 총 7 페이지 )


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초록(외국어)
We investigated the antithrombotic effect of Acorus gramineus Soland (A. gramineus) from Korea and Acorus tatarinowii Schott (A. tatarinowii) from China in a rat model of arterial thrombosis induced by ferric chloride (FeCl3). Thirty minutes prior to a 35% FeCl3 application, Sprague Dawley rats were intraperitoneally injected with saline, A. gramineus and A. tatarinowii (100 mg/kg), respectively. Occlusion time of rats injected with A. gramineus was delayed significantly compared to that of the vehicle and A. tatarinowii. Thrombus weight was meaningfully decreased in rats injected with A. gramineus compared to the vehicle. Additionally, A. gramineus inhibited collagen fiber damage in vessel compared to the vehicle, but A. tatarinowii did not show a significant effect. Our results show that A. gramineus and A. tatarinowii from the same genus have different antithrombotic effects, and especially A. gramineus has a better antithrombotic effect than A. tatarinowii.

논문정보
  • - 주제 : 의약학분야 > 약화학
  • - 발행기관 : 한국생약학회
  • - 간행물 : Natural Product Sciences, 19권 3호
  • - 발행년도 : 2013
  • - 페이지 : pp.251-257 ( 총 7 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2014-500-001880808
저널정보
  • - 주제 : 의약학분야 > 약화학
  • - 성격 : 학술지
  • - 간기 : 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : - / SCOPUS
  • - ISSN : 1226-3907
  • - 수록범위 : 1995–2021
  • - 수록 논문수 : 1174