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> 한국키틴키토산학회 > 한국키틴키토산학회지 > 20권 2호

Antioxidant Effect of Fucoidan from Miyeokgui, Marine Alga in Zebrafish Model

Antioxidant Effect of Fucoidan from Miyeokgui, Marine Alga in Zebrafish Model

( Hye Won Yang ) , ( Jae Young Oh ) , ( Eun A Kim ) , ( Seo Young Kim ) , ( Jae Il Kim ) , ( You Jin Jeon )

- 발행기관 : 한국키틴키토산학회

- 발행년도 : 2015

- 간행물 : 한국키틴키토산학회지, 20권 2호

- 페이지 : pp.123-130 ( 총 8 페이지 )


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논문제목
초록(외국어)
Fucoidan, extracted from Undaria pinnatifida (U. pinnatifida), has been extensively studied because of its wide biological activities. However, antioxidative activities of fucoidan extracted from Miyeokgui have not been yet examined in the zebrafish model. Therefore the present study was designed to evaluate in vitro and in vivo studies on antioxidative activities of fucoidan extracted from Miyeokgui by using 0.1 M hydrochloric acid (MAF). We found that MAF reduced the production of intracellular reactive oxygen species (ROS) in the 2, 2’-azobis dihydrochloride (AAPH) induced oxidative stress in Vero cells. Furthermore, the protective effect of MAF was examined against AAPH-induced oxidative stress in zebrafish model. MAF possesses a protective effect against AAPH-induced toxicity in zebrafish embryos. In addition, MAF significantly reduced AAPH-induced ROS production and lipid peroxidation in zebrafish embryos. These results proved that MAF has antioxidant activities both in vitro Vero cells and in vivo zebrafish model.

논문정보
  • - 주제 : 자연과학분야 > 생물
  • - 발행기관 : 한국키틴키토산학회
  • - 간행물 : 한국키틴키토산학회지, 20권 2호
  • - 발행년도 : 2015
  • - 페이지 : pp.123-130 ( 총 8 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2015-400-001904244
저널정보
  • - 주제 : 자연과학분야 > 생물
  • - 성격 : 학술지
  • - 간기 : 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : -
  • - ISSN : 1229-4160
  • - 수록범위 : 1996–2021
  • - 수록 논문수 : 1087