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> 한국보건정보통계학회 > 보건정보통계학회지 > 41권 1호

Original Article : Inter-Rater Reliability of Carotid Intima-Media Thickness Measurements in a Multicenter Cohort Study

Original Article : Inter-Rater Reliability of Carotid Intima-Media Thickness Measurements in a Multicenter Cohort Study

( Jung Hyun Lee ) , ( Dong Phil Choi ) , ( Jee Seon Shim ) , ( Dae Jung Kim ) , ( Sung Ha Park ) , ( Hyeon Chang Kim )

- 발행기관 : 한국보건정보통계학회

- 발행년도 : 2016

- 간행물 : 보건정보통계학회지, 41권 1호

- 페이지 : pp.49-56 ( 총 8 페이지 )


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논문제목
초록(외국어)
Objectives: Carotid intima-media thickness (CIMT) and the presence of carotid artery plaque are widely used as preclinical markers of atherosclerosis. Due to operator dependency in measuring CIMT, it is important to evaluate the reliability of measuring CIMT and plaque between centers in a multicenter study. The purpose of this study is to evaluate the inter-rater reliability of CIMT and plaque presence among three clinical centers of the Cardiovascular and Metabolic Disease Etiology Research Center (CMERC). Methods: Twenty people without known cardiovascular disease (age 37-64) were enrolled during 2014-2015, and their left and right carotid arteries were examined repeatedly with ultrasonography for CIMT measurements at three clinical centers according to a predetermined protocol. Maximum and mean values of CIMT at distal common carotid artery were recorded. Plaque presence at a carotid artery was checked by an operator. The reliability of CIMT and carotid plaque presence was assessed using an intraclass correlation coefficient (ICC) and kappa statistics, respectively. Results: Calculated ICC was 0.647 (95% CI: 0.487-0.779) for maximum CIMT, and 0.758 (95% CI: 0.632-0.854) for mean CIMT. In Bland Altman plot, most observed values were distributed within mean difference ±1.96 SD ranges. Kappa statistics of plaque presence between two centers were 0.304 (center 1 and 2), 0.507 (center 1 and 3), and 0.606 (center 2 and 3), respectively, while Fleiss kappa for overall agreement was 0.445. Conclusions: The inter-rater reliability of CIMT measurements among three clinical centers turned out to be high, and the agreement of measuring carotid plaque presence was fair.

논문정보
  • - 주제 : 의약학분야 > 예방의학및보건학
  • - 발행기관 : 한국보건정보통계학회
  • - 간행물 : 보건정보통계학회지, 41권 1호
  • - 발행년도 : 2016
  • - 페이지 : pp.49-56 ( 총 8 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2016-510-000711855
저널정보
  • - 주제 : 의약학분야 > 예방의학및보건학
  • - 성격 : 학술지
  • - 간기 : 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : -
  • - ISSN : 2465-8014
  • - 수록범위 : 1976–2021
  • - 수록 논문수 : 746