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> 한국공업화학회 > 한국공업화학회 연구논문 초록집 > 2017권 1호

2P-369 Synthesis and evaluation of natural compounds-peptide derivatives as potential anti-wrinkle agents

2P-369 Synthesis and evaluation of natural compounds-peptide derivatives as potential anti-wrinkle agents

이혜숙 , 김한영

- 발행기관 : 한국공업화학회

- 발행년도 : 2017

- 간행물 : 한국공업화학회 연구논문 초록집, 2017권 1호

- 페이지 : pp.345-345 ( 총 1 페이지 )


학술발표대회집, 워크숍 자료집 중 1,2 페이지 논문은 ‘요약’만 제공되는 경우가 있으니,

구매 전에 간행물명, 페이지 수 확인 부탁 드립니다.

1,000
논문제목
초록(외국어)
As aging process continues in human skin, collagen production is reduced and fragmentation is increased, which is initiated by matrix metalloproteinase-1. Elastase is a degrading enzyme present in the dermis, and plays a role in the degradation of the ECM, which contains elastin. We developed natural compounds-peptides derivatives as potential anti-wrinkle agents which combined anti-oxidative small molecule and peptides have an effect on collagenase or elastase active sites. We synthesized 100 natural compounds-peptides derivatives by solid-phase peptide synthesis method. We evaluated anti-wrinkle activities of these natural compounds-peptide derivatives in vitro. Collagen synthesis assay, collagenase activity inhibition assay and elastase activity inhibition assay were performed using human fibroblast. Further efforts to verify their anti-wrinkle activities in vivo and their application for cosmetics are underway.

논문정보
  • - 주제 : 공학분야 > 화학공학
  • - 발행기관 : 한국공업화학회
  • - 간행물 : 한국공업화학회 연구논문 초록집, 2017권 1호
  • - 발행년도 : 2017
  • - 페이지 : pp.345-345 ( 총 1 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2018-500-003822535
저널정보
  • - 주제 : 공학분야 > 화학공학
  • - 성격 : 학술발표
  • - 간기 : 반년간
  • - 국내 등재 : -
  • - 해외 등재 : -
  • - ISSN :
  • - 수록범위 : 1990–2020
  • - 수록 논문수 : 44807