글로버메뉴 바로가기 본문 바로가기 하단메뉴 바로가기

논문검색은 역시 페이퍼서치

> 대한화장품학회 > 대한화장품학회지(J. Soc. Cosmet. Scientists Korea) > 24권 1호

Chestnut Extracts as new Anti-aging agent

Chestnut Extracts as new Anti-aging agent

김범준 ( Beom-jun Kim ) , 김정하 ( Jeong-ha Kim ) , 김현포 ( Hyun-pyo Kim ) , 허문영 ( Moon-young Heo )

- 발행기관 : 대한화장품학회

- 발행년도 : 1998

- 간행물 : 대한화장품학회지(J. Soc. Cosmet. Scientists Korea), 24권 1호

- 페이지 : pp.113-126 ( 총 14 페이지 )


학술발표대회집, 워크숍 자료집 중 1,2 페이지 논문은 ‘요약’만 제공되는 경우가 있으니,

구매 전에 간행물명, 페이지 수 확인 부탁 드립니다.

5,400
논문제목
초록(외국어)
Inner nutshell of Castanea crerata(chestnut) has been used as an anti-aging and anti-wrinkle agent from the ancient time in east Asia. In order to develop new anti-aging and anti-wrinkle, ethanolic extract of inner nutshell of Castanea crenata(Cor-285) was prepared and various biological activities were evaluated. Cor-285 showed potent anti-oxidant activity. Especially, Cor-285 possessed potent free radical scavenging activity in vitro(lC50:7.6㎍/ml) compared to gallic acid(IC50:12.5㎍/ml). Cor-285 showed the preventive effect against UV-induced cytotoxicity of fibroblast at concentration of 25-250㎍/ml. When Cor-285 was evaluated for its anti-allergic activity, it effectively inhibited histamine release from mast cells induced by compound 48/80(86% inhibition at 10mg/ml). The inhibitory activity was stronger than that of glycyrrhizinate. Cor-285 also showed in vivo inhibition against delayed hypersensitivity as well as croton-oil induced ear edema in mice when topically applied. These results strongly suggest that Cor-285 may reduce immunoregulatory/inflammatory skin trouble. From the attempts to isolate the scavenger, were isolated. In a clinical trial of twenty healthy volunteers with aged skin, 6 weeks application of Cor-285(3% cream) decreased wrinkle about 26% and increased moisturizing 20% on the skin. All of these results indicate that Cor-285 may be an effective anti-aging and anti-wrinkle agent.

논문정보
  • - 주제 : 의약학분야 > 피부과학
  • - 발행기관 : 대한화장품학회
  • - 간행물 : 대한화장품학회지(J. Soc. Cosmet. Scientists Korea), 24권 1호
  • - 발행년도 : 1998
  • - 페이지 : pp.113-126 ( 총 14 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2019-500-001626637
저널정보
  • - 주제 : 의약학분야 > 피부과학
  • - 성격 : 학술지
  • - 간기 : 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : -
  • - ISSN : 1226-2587
  • - 수록범위 : 1970–2021
  • - 수록 논문수 : 1138