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> 대한본초학회 > 대한본초학회지(본초분과학회지) > 35권 3호

배합 비율에 따른 황련과 황금의 혼합 전탕액 및 개별 전탕 혼합액 내 성분 함량 분석

Quantitative analysis of the marker compounds in the decoctions of Coptis chinensis-Scutellaria baicalensis at different proportion produced by ‘Mixed decoction’ and ‘Single decoction mixture’

김한영 ( Han-young Kim ) , 김정훈 ( Jung-hoon Kim )

- 발행기관 : 대한본초학회

- 발행년도 : 2020

- 간행물 : 대한본초학회지(본초분과학회지), 35권 3호

- 페이지 : pp.33-45 ( 총 13 페이지 )


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5,300
논문제목
초록(외국어)
Objective : The present study aimed to evaluate the change of the content of 7 active components in decoctions produced by various proportional pairs of Coptis chinensis Franch and Scutellaria baicalensis Georgi in ‘Mixed decoction (MD)’ and ‘Single decoction mixture (SDM)’. Methods: The samples of MDs were prepared by decocting C. chinensis: S. baicalensis with the ratios of 10 g:10 g, 10 g:20 g, and 20 g:10 g. Those of SDMs were prepared by blending each single decoction from C. chinensis and S. Baicalensis with the ratios of 1:1, 1:2, and 2:1. The samples were evaluated by high-performance liquid chromatography with statistical analyses. Results: The analytical methods, which were optimized and validated, were reliably applied to present research. The content of all components in both MDs and SDMs at C. chinensis: S. baicalensis = 1:1 ratio were reduced compared with single herb decoction. The components from each compositional herb in MDs were proportionally increased with the ratio of original herb increased, but inversely proportional to paired herb. The contents of components in MDs were significantly lower than those in SDMs at all ratios, except for high content of baicalin at C. chinensis: S. baicalensis = 2:1. Conclusion: It was concluded that MDs and SDMs as well as the proportions of herbs could affect the contents of the components from original herbal medicines. These results provide the information for the quality control of herbal medicine combined C. chinensis with S. baicalensis.

논문정보
  • - 주제 : 의약학분야 > 기초한의학
  • - 발행기관 : 대한본초학회
  • - 간행물 : 대한본초학회지(본초분과학회지), 35권 3호
  • - 발행년도 : 2020
  • - 페이지 : pp.33-45 ( 총 13 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2021-500-000838727
저널정보
  • - 주제 : 의약학분야 > 기초한의학
  • - 성격 : 학술지
  • - 간기 : 격월
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : -
  • - ISSN : 1229-1765
  • - 수록범위 : 1986–2021
  • - 수록 논문수 : 1636