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> 대한미용학회 > 대한미용학회지 > 16권 4호

UVA 조사된 HaCaT각질형성세포에서 큰금계국 메탄올추출물의 광노화에 대한 보호 효과

Protective Effects of Coreopsis lanceolate L. Methanol Extract on UVA-induced Photoaging in HaCaT Keratinocytes

오창종 ( Chang Jong Oh ) , 이재순 ( Jae Soon Lee ) , 김영철 ( Young Chul Kim )

- 발행기관 : 대한미용학회

- 발행년도 : 2020

- 간행물 : 대한미용학회지, 16권 4호

- 페이지 : pp.317-322 ( 총 6 페이지 )


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초록(외국어)
In order to investigate the protective effects of Coreopsis lanceolate L. methanol extract (CLME) on UVA-induced photoaging in HaCaT human keratinocytes, type I procollagen production, hyaluronic acid (HA) production, and reactive oxygen species (ROS) were investigated in UVA-irradiated HaCaT cells. Treatment with 100 μg/mL CLME increased type I procollagen production by 16.6% (p<0.001), 14.0% (p<0.001), and 26.9% (p<0.001) in 10, 20, and 30 mJ/cm2 UVA-irradiated HaCaT cells, respectively, which were higher than the formation of ascorbic acid (AA) (5.9%, 7.2%, and 17.6%, respectively). Similarly, treatment with 100 μg/mL CLME increased the HA production by 27.3% (p<0.001), which was higher than that of AA (24.9%, p<0.001), in 30 mJ/cm2 UVA-irradiated HaCaT cells. Furthermore, treatment with 100 μg/mL CLME decreased the ROS production by 24.2% (p<0.001), which was higher than that of AA (17.2%, p<0.001), in 30 mJ/cm2 UVA-irradiated HaCaT cells. The results obtained in this study showed that CLME has protective ability on UVA-induced photoaging in HaCaT cells.

논문정보
  • - 주제 : 자연과학분야 > 가정
  • - 발행기관 : 대한미용학회
  • - 간행물 : 대한미용학회지, 16권 4호
  • - 발행년도 : 2020
  • - 페이지 : pp.317-322 ( 총 6 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2022-500-000287384
저널정보
  • - 주제 : 자연과학분야 > 가정
  • - 성격 : 학술지
  • - 간기 : 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : -
  • - ISSN : 2508-8009
  • - 수록범위 : 2005–2022
  • - 수록 논문수 : 720