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> 대한미용학회 > 대한미용학회지 > 16권 4호

저온숙성 복합한약재 추출물의 항산화능, 항균활성 및 NO 생성 억제능

Antioxidant, Antimicrobial and NO Production Inhibitory Activities of Mixed Medicinal Herb Extracts Aged at Low Temperature in Mineral Water

김미경 ( Mee Kyung Kim )

- 발행기관 : 대한미용학회

- 발행년도 : 2020

- 간행물 : 대한미용학회지, 16권 4호

- 페이지 : pp.343-350 ( 총 8 페이지 )


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4,500
논문제목
초록(외국어)
In order to investigate the possibility of using low-temperature aged mixed medicinal herb extract (Angelica gigas Nakai, Rechmannia glutinosa Libosch, Paeonia lactiflora Pall, Cnidium officinale Makino, Scutellaria baicalensis Georgi) as a material for beauty foods and herbal cosmetics, in the present study, we investigated the yield, total polyphenol content, antioxidant and NO production inhibitory effects of low-temperature aged mixed extracts. The mixed medicinal herbs was precipitated in mineral water and aged at low temperatures. After that, the supernatant was MLE and the precipitate was extracted with water (MLWE) and ethanol (MLEE). As a result, the yield of each extract was much higher in MLE (64.96%) than MLWE (8.30%) and MLEE (7.04%), the total polyphenol content was 283.9 mg TAE/g in MLEE, which was 2.2~3.8 times higher than that in MLE and MLWE. Antioxidation measurements showed that the radical scavenging abilities of DPPH (95.1%) and ABTS (96.7%) were significantly higher at 1,000 μg/mL concentration. In antimicrobial activity test, the MLEE showed a high antimicrobial activity against P. acnes. The cytotoxic concentrations of low temperature aged mixed medicinal herb extracts showed cell viability above 90% at concentrations 100 μg/mL and inhibition of NO production by 52.6% at 100 μg/mL for MLEE. From the results of this study, the ethanol extract of low temperature aged mixed medicinal herb showed a significant effect on the total polyphenol content, antioxidant, and inhibition of NO. Therefore, it is believed that the ethanol extract of low temperature aged mixed medicinal herb can be used as a material for beauty foods and herbal cosmetics.

논문정보
  • - 주제 : 자연과학분야 > 가정
  • - 발행기관 : 대한미용학회
  • - 간행물 : 대한미용학회지, 16권 4호
  • - 발행년도 : 2020
  • - 페이지 : pp.343-350 ( 총 8 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2022-500-000287415
저널정보
  • - 주제 : 자연과학분야 > 가정
  • - 성격 : 학술지
  • - 간기 : 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : -
  • - ISSN : 2508-8009
  • - 수록범위 : 2005–2022
  • - 수록 논문수 : 720