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> 대한미용학회 > 대한미용학회지 > 16권 4호

애플망고 가지 추출물의 항산화 활성 및 대식세포내의 iNOS, COX-2의 염증인자 발현 저해 효과

The Antioxidant Activity of Mangifera indica L. var. irwin Branches Extracts and the Inhibitoty Effect of Inflammatory Factors of iNOS, COX-2 in Macrophages

유단희 ( Dan Hee Yoo ) , 이인철 ( In Chul Lee )

- 발행기관 : 대한미용학회

- 발행년도 : 2020

- 간행물 : 대한미용학회지, 16권 4호

- 페이지 : pp.357-365 ( 총 9 페이지 )


학술발표대회집, 워크숍 자료집 중 1,2 페이지 논문은 ‘요약’만 제공되는 경우가 있으니,

구매 전에 간행물명, 페이지 수 확인 부탁 드립니다.

4,500
논문제목
초록(외국어)
In the present study, anti-oxidant and anti-inflammation activities of distilled water extract (AMBW) and 70% ethanol extract (AMBE) of Mangifera indica L. var. irwin branches were investigated. The total polyphenol content of M. indica L. var. irwin branch extracts was 523.24±1.03 (AMBW), 556.15±2.80 (AMBE) mg TAE/100 g dry weight. The anti-oxidant activity of the extracts was estimated using electron donation and scavenging activity of 2,2'-azino bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) free radicals which increased with concentration. To measure the anti-inflammation effects, RAW 264.7 cells treated with lipopolysaccharide were used. The cell viability of M. indica L. var. irwin branches extracts in RAW 264.7 cells was measured with 3-[4,5-dimethyl-thiazol-2-yl]-2,5- diphenyl-tetrazoliumbromide (MTT) assay. The results of MTT assay showed more than 95% refers to cell viability at the 100 μg/mL of AMBW and AMBE. The production of nitric oxide (NO) analyzed by griess assay decreased with increasing concentration of the extracts. The mRNA expression toward inducible NO synthase and cyclooxygenase-2 was confirmed using reverse transcription-polymerase chain reaction and inhibited the treated M. indica L. var. irwin branches extracts. In conclusion, M. indica L. var. irwin branch extracts were confirmed to have antioxidant and anti-inflammation properties and can be used as a natural ingredient of cosmetic materials.

논문정보
  • - 주제 : 자연과학분야 > 가정
  • - 발행기관 : 대한미용학회
  • - 간행물 : 대한미용학회지, 16권 4호
  • - 발행년도 : 2020
  • - 페이지 : pp.357-365 ( 총 9 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2022-500-000287435
저널정보
  • - 주제 : 자연과학분야 > 가정
  • - 성격 : 학술지
  • - 간기 : 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : -
  • - ISSN : 2508-8009
  • - 수록범위 : 2005–2022
  • - 수록 논문수 : 720