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P001 : Cold atmospheric plasma prevents wrinkle formation via an anti-aging process

P001 : Cold atmospheric plasma prevents wrinkle formation via an anti-aging process

( Sang Gyu Hwanga ) , ( Jung Ho Kim ) , ( Soo Youn Jo ) , ( Young Jae Kim ) , ( Hyoung Min Na ) , ( Chong Hyun Won )

- 발행기관 : 대한피부과학회

- 발행년도 : 2020

- 간행물 : 프로그램북(구 초록집), 72권 1호

- 페이지 : pp.379-379 ( 총 1 페이지 )


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구매 전에 간행물명, 페이지 수 확인 부탁 드립니다.

무료
논문제목
초록(외국어)
Background: Cold atmospheric plasma is a material that generates free radicals through the ionization of air. Despite the application of this material in various medical fields, the precise mechanism underlying its effect at the cellular level is not understood fully. To date, it is known to stimulate the expression of anti-oxidant transcription factors such as nuclear factor erythroid 2-related factor 2 (Nrf2), forkhead box class O 3a (FOXO3a). Objectives: In this study, we aimed to assess whether and how cold atmospheric plasma affects damaged cells, particularly after exposure to UV radiation. Methods: Human dermal fibroblast primary cells from adult skin tissue were treated with the cold atmospheric plasma(CAP), UV exposure. Quantitative assessment is done by western blot analysis using various primary antibodies. Fluorescence images were obtained by immunocytochemistry. Results: Cold atmospheric plasma can promote mitochondrial health by controlling the stability of the membrane potential of mitochondria against UV radiation. Moreover, cold atmospheric plasma prevented senescence in fibroblasts exposed to UV radiation through the upregulation of p53. Cold atmospheric plasma also exhibited hormetic effects on MMP and collagen in senescent fibroblasts exposed to UV radiation. Conclusion: In conclusion, cold atmospheric plasma treatment not only protected fibroblasts from free radicals, but also repressed the aging of these cells in a UV-radiation-induced aging process.

논문정보
  • - 주제 : 의약학분야 > 피부과학
  • - 발행기관 : 대한피부과학회
  • - 간행물 : 프로그램북(구 초록집), 72권 1호
  • - 발행년도 : 2020
  • - 페이지 : pp.379-379 ( 총 1 페이지 )
  • - UCI(KEPA) :
저널정보
  • - 주제 : 의약학분야 > 피부과학
  • - 성격 : 학술발표
  • - 간기 : 반년간
  • - 국내 등재 : -
  • - 해외 등재 : -
  • - ISSN :
  • - 수록범위 : 1947–2021
  • - 수록 논문수 : 24140