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논문검색은 역시 페이퍼서치

보건정보통계학회지검색

Journal of Health Informatics and Statistics


  • - 주제 : 의약학분야 > 예방의학및보건학
  • - 성격 : 학술지
  • - 간기: 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : -
  • - ISSN : 2465-8014
  • - 간행물명 변경 사항 : 한국보건통계학회지(~2003) → 한국보건정보통계학회지(2004~)
논문제목
수록 범위 : 36권 1호 (2011)

What is the Clinical Trial?

( Young Jack Lee )
5,400
초록보기
No drug is a drug until it is proven safe and effective (safety first-emphasis added). All drugs in these days have been approved by government authority after a series of clinical trials. Today, clinical trials have begun in Korea only recently. Nevertheless Korea is fast becoming a popular destination for multinational clinical trials. Korea Food and Drug Administration has defined that clinical trial is any investigation in human subjects to study effects of investigational products. Clinical trial is a process that must strictly abide by rules, regulations and study plans. Clinical trial of new drug candidate has very high chance of failure and thus is very difficult. Finally, clinical trial is scientific experiment within frame of ethics and respect for human rights. Technical core of this last point is statistical principles of minimizing bias and design of experiment. Final product of clinical trials is statistical inference about effects of investigational products in human body. So, answer to "What is the clinical trial?" is "a statistically valid medical inference- making process for medicine."

건강보험 약품비 증가의 주요 요인분석

최윤정 ( Yoon Jung Choi ) , ( Joel I. Shalowitz )
4,500
초록보기
Objectives: Rising pharmaceutical expenditure in Korea has become a major concern of policy makers over recent years. To reduce the growth in pharmaceutical expenditure, we need to analyze the major determinants of pharmaceutical spending. We defined three drug types: new, abandoned and existing drugs. The existing drugs are composed of two aspects - the changes in price and quantity Methods: The data was extracted from the Korean National Health Insurance (NHI) claims data. The data was based on every prescription product dispensed to beneficiaries of the NHI between 2002 and 2006. Results: The contribution of the new drugs was 22~48% in the first half of 2002~2006. Abandoned products were associated with cost decrease. The contribution of the existing products impacted on most of the growth of the paired years in 2002~2006. The existing product spending broke down into price and quantity effects. Price Changes (PC) had the range of -1.7 to 0.5. Quantity Changes (QC) was more than 9% in 2002~2006. Recently, the number of prescription affected more than the mix of prescription on the QC. Conclusions: The results of this study provide evidence for making the political decision that the pharmaceutical regulations in Korea need to be focused on the volume control.

The Effects of Water Education Program of High School Students: 8 Months Experimental Study

( Yon Ho Jee ) , ( Dock Won Son ) , ( Da Seul Kim )
5,300
초록보기
Objectives: Water is essential to human body. This study was conducted to evaluate the effects of water education by analyzing differences in knowledge of water on human body, attitudes, and behaviors before and after water education. Methods: The study subjects included 138 girls (4 classes) from Yale Girls` High School, Seoul, Korea. Self-administered questionnaires were completed three times: prior to water education, at 1 week and at 8 months after water education. Water education was delivered using videos and PowerPoint slides over a period of 3 days. Changes in knowledge, attitudes, and behaviors towards water scarcity before and after water education were analyzed by Chi-square and t-tests. Results: Compared to the control group, the experimental group found to have greater knowledge of water and a better understanding of the effects of water on the human body. Changes in knowledge (p = 0.008) and attitude (p = 0.041) towards water remained at a significant level 8 months after water education; however, no changes were found in behavior towards water scarcity after water education. Conclusions: The water education program effectively improved the knowledge and attitudes towards water scarcity during a short period of time. Further studies are needed to determine long-term effects of water education using a large number of study subjects.

체질량지수와 유방암발생의 관련성

임선미 ( Sun Mi Lim ) , 허남욱 ( Nam Wook Hur ) , 김현창 ( Hyun Chang Kim ) , 강대용 ( Dae Ryong Kang ) , 서일 ( Il Suh )
5,100
초록보기
Objectives: This study investigated the association between body mass index (BMI) (and its change) and risk of breast cancer in Korea women by age. Methods: Participants were 64,149 women aged 35~59 years at the baseline (1990~1992) of the Korea Medical Insurance Corporation study. They were stratified as 44,923 women aged 37~47 years and 19,226 women aged 48~61 years by age at year 1992. BMI change was defined as BMI at 1994 minus baseline BMI. Baseline BMI was categorized quartile and first quartile used as reference group for the analysis. BMI change was categorized quartile and second quartile used as reference group for the analysis. Hazard ratio (HR) calculated using Cox`s proportional hazard model. Results: Baseline BMI and breast cancer risk were not associated in women aged < 48 (HR = 0.83, p for trend = 0.182 for Q4 vs Q1), but associated in women aged ≥ 48 (HR = 2.08, p for trend = 0.002 for Q4 vs Q1). However, BMI change was not associated with breast cancer risk in either age group. Conclusions: These results suggest that obesity may be a risk factor breast cancer in premenopausal women but not in post menopausal women.

암전문가와 가정의의 암환자 케어를 위한 암정보 필요에 대한 연구

서화정 ( Hwa Jeong Seo ) , 강세나 ( Se Na Kang ) , 이명희 ( Myung Hee Lee ) , 장윤정 ( Yoon Jung Chang )
5,100
초록보기
Objectives: Both oncologists and family physicians have involved in care of cancer patients, and their knowledge and attitudes towards cancer influence cancer patient care. This study aims to compare knowledge, attitudes, and practice of cancer care between oncologists and family physicians. Methods: Total 102 questions related to cancer information needs and experiences of cancer patient cancer were asked to members of Korean Cancer Association and Korean Academy of Family Medicine through an email. Results: There were total 174 oncologists and 326 family physicians participated in the study, and their mean age and experience of practice were 43 and 37.2 respectively. Oncologists and family physician had different attitudes and preference regarding patients` informational needs related to ``adverse effects of chemotherapy`` and ``disease management other than cancer.`` It was statistically significant (P < 0.05). In addition, usage of cancer information was significantly different between the groups. They used ``cancer diagnosis and treatment guideline``, ``updated knowledge and experts opinion``, ``results of outcome studies``, and ``continuing education for cancer management`` information differently. Conclusions: This study was to investigate necessity and the importance of cancer information among oncologists and family physicians. Results of this study would be good reference for developing a database of cancer information for oncologists and family physicians so they could use cancer related information efficiently.

근로자 건강보호목표수준 제안을 위한 이소프렌의 용량-반응 평가 적용연구

김현지 ( Hyun Ji Kim ) , 신동천 ( Dong Chun Shin ) , 임영욱 ( Young Wook Lim ) , 양지연 ( Ji Yeon Yang ) , 이용진 ( Yong Jin Lee )
5,300
초록보기
Objectives: We investigated the method of application of dose-response assessment of domestic industry to present occupational health protection target level. Methods: Melnick`s study data and NTP (National Toxicology Program) data using data, deterministic methods and probabilistic approaches were compared. Results: As a result of the dose-response assessment based on Melnick`s data and NTP data, RfC (Reference Concentration) was calculated as 1.3 ppm (determined by the NTP data). So in this paper they were determined at the health protection target level of 1.3 ppm. Final results according to the type of data, the dose-response assessment method are determined. Conclusions: Dose-response assessment based on Isoprene revealed that most important thing is toxicity endpoint to suggest health protection target level by utilizing dose-response assessment to the domestic workplace.

일 보건대학 재학생의 헌혈실태와 헌혈부적격 영향요인 조사

박복남 ( Boc Nam Park ) , 서문숙 ( Moon Sook Suh ) , 양병선 ( Byong Seon Yang )
5,600
초록보기
Objectives: The purposes of this study were to survey of blood donors and analysis factors affecting of unqualified donors at health college. Methods: We collected data 213 students of J health college in J city by using the questionnaire from December 5 to December 7, 2007. The collected data were analyzed using the SPSS 11.5 program with t-test, Chi-square and logistic regression. Results: The total number of blood donors was 473, among which 221 (46.7%) were qualified as eligible donors and 252 (53.35%) were unqualified at 2006. And the number of qualified as donors was 288 (43.0%) by the total number of 670 and among which 382 (57.0%) were unqualified at 2007. The unqualification rates were 80.5% (2006) and 59.0% (2007) for the Low specific gravity of blood. Factors affecting deferral donation were gender (OR = 6.76, p = .013), grade (OR = .04, p < .0001), department (OR = 3.38 p = .004), age (OR = 4.92, p < .0001), BMI (OR = 2.70, p = .027), regular meals (OR = 2.12, p = .012), after menstrual period(OR = 2.20, p = .017) and experience of donation (OR = 1.93, p = .019). Conclusions: It is necessary to educate donor eligibility criteria for college students. We must develop health education program to maintain regular health habits.

전자의무기록에서 서식작성을 위한 접근권한관리시스템 구현

김정학 ( Jeong Hak Kim ) , 채영문 ( Young Moon Chae ) , 이기한 ( Ki Han Lee ) , 이병화 ( Byung Hwa Lee )
5,500
초록보기
Objectives: With introducing electronic medial record systems (EMRS), the private information protection of patient has been an issue of hospitals, and system developments for accessing to patients` personal information are required to control the system with effect. This study aims to realize an access rights system for EMRS using the delphi technique and business rules management system (BRMS). Methods: The consensus of access rights was conducted by 41 experts from a task force team of EMR development. The access rights system has been developed by constructing DTD, RuleML and converting XSLT based on the consensus, and evaluated by alpha test and records logged for eight month period. Results: Write access to the EMRS are provided only nurses and doctors, and in case of the referral department, it is investigated that their information is allowed to be input and modified by the referral department only. For a copy, printing out is allowed to the medical records department only, and nobody has an authority to delete any data. We found that the access rights management system worked well for patients` personal information protection on general hospitals` EMRS. Conclusions: We propose an effective personal information protection system that can apply to general hospital EMRS through this study. Also, for the system success, there is a need for monitoring of user convenience and availability.

두 모집단 비율 비교에서 상대위험도와 승산비에 기초한 표본크기 추정

조성경 ( Seong Kyung Cho ) , 강위창 ( Wee Chang Kang ) , 채성산 ( Seong San Chae )
5,300
초록보기
Objectives: We suggested a method of calculating sample size to compare the relative risk or the odds ratio, in which we used the asymptotic distribution of the logarithm of its estimator. The empirical power of the proposed sample size was investigated through simulation studies. Methods: The proposed formula of calculating sample size was derived based on the score test statistic induced by the asymptotic distribution of the logarithm of the estimated relative risk or the estimated odds ratio. Through some simulation studies the empirical power of the proposed sample size was compared with that of the sample size formulated from the asymptotic distribution of the difference between two estimated proportions. Results: When true relative risks or odds ratios were greater than 1, the power of the proposed sample size was more close to the intended power than that of the sample size obtained by the commonly used formula in the comparison of two proportions. Conclusions: When the comparison of two proportions should be carried out with the relative risk or odds ratio, the proposed formulas gave us more valid sample size than the formula derived by the test statistic of the difference between two proportions.

공공부문 u-Health 서비스 효과성 분석

이재국 ( Jae Gook Lee ) , 류시원 ( See Won Ryu ) , 송태민 ( Tae Min Song )
5,400
초록보기
Objectives: This study was to evaluate the effectiveness of u-Health service in public area based on an extended technology acceptance model (TAM), and test the acceptance behavior of the u-Health service. Methods: Data were surveyed from the experienced of u-Health service for three months (7.1~9.30, 2010) in Seocho city, Seoul, Korea. We measured personal innovativeness, subjective norm, output quality, and perceived playfulness with likert-scale multiple items, perceived usefulness, perceived ease of use, attitude toward use, and the behavioral intention as mediator variables; and actual use and u-Health loyalty were used as dependent variables. Results: The results were as follows; Service quality of u-Health in public area was the significant key factor to the usefulness, the ease of use. Most of the hypotheses from the original model of TAM were supported. Behavioral intention significantly affected actual and continuing use of u-Health service. TAM variables mediated between independent variables and dependent variables. Conclusions: We evaluated u-Health services for public health management by survey data from the users. The quality of u-Health service was significantly effective by controlling the other influencing factors. Results will be useful for decision making about u-Health service in public area.
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